马吲哚的作用与功效_马吲哚说明书

NMPA批准适应症

【适应症及用法用量】

适用于治疗非器质性单纯性肥胖症，以辅助控制饮食及运动疗法的减肥作用。

剂型	规格
片剂	——

用法用量:: 人群: 成人

给药途径: 口服

用法用量详情: 一般剂量为一次0.5mg，一日1次，饭前服用。一日最大剂量不超过1.5mg，分2～3次饭前服用，8～12周为一个疗程。

【注意事项】: 1.糖尿病患者使用可能影响胰岛素及降血糖药物效果，故在治疗期间应监测患者代谢状况，必要时应适当调整胰岛素及降糖药物剂量。高血压患者使用时，应注意血压监测。2.可能增加外源性儿茶酚胺效应，故使用肾上腺素类药物应密切监测患者心血管系统反应。3.不得超过规定最高服药量以试图增效，正常疗程一般为2～3个月。服用前后宜作血象、肝、肾功能检查。

【禁忌症】: 1.对本药过敏者。; 2.严重肝、肾功能不全者。; 3.严重心功能不全(包括心律不齐)者。; 4.严重高血压患者。; 5.过度兴奋者。; 6.青光眼患者。; 7.器质性病变引起肥胖的患者。; 8.有药物滥用史者(国外资料)。; 9.儿童。; 10.妊娠期妇女。; 11.哺乳期妇女。

【参考文献】: 1.说明书-DA TSCAN(R) IV injection, ioflupane I 123 IV injection(GE Healthcare, Arlington Heights, IL); 2.说明书-Meridia(R), sibutramine hydrochloride monohydrate(Knoll Pharmaceutical Company, Mount Olive, NJ); 3.说明书-Sanorex(R), mazindol tablets(Sandoz Pharmaceuticals, East Hanover, NJ, USA); 4.说明书-Sanorex(R), mazindol(Sandoz Pharmaceuticals Corporation, East Hanover, NJ); 5.说明书-VYVANSE(TM) oral capsules, lisdexamfetamine dimesylate oral capsules(New River Pharmaceuticals,Inc, Blacksburg, VA); 6.说明书-马吲哚片; 7.文献资料-Acta Neurol Scand,1979; 8.文献资料-Br Med J,1983; 9.文献资料-Clin Obstet Gynecol,2002; 10.文献资料-Curr Ther Res,1977; 11.文献资料-Drug Metab Dispos,1979; 12.文献资料-Med J Aust,1975; 13.文献资料-Practitioner,1977; 14.文献资料-Praxis,1976; 15.文献资料-Rocky Mountain Med J,1974; 点击展开全部文献

【安全级别及用药方案】: 慎用本药尚未对老人用药给予特殊说明，老人用药剂量一般推荐从最小剂量开始，根据《中国药典》规定：60-80岁的老年人约为成人剂量的3/4；80岁以上的老年人约为成人剂量的2/3。

【参考文献】: 1.说明书-DA TSCAN(R) IV injection, ioflupane I 123 IV injection(GE Healthcare, Arlington Heights, IL); 2.说明书-Meridia(R), sibutramine hydrochloride monohydrate(Knoll Pharmaceutical Company, Mount Olive, NJ); 3.说明书-Sanorex(R), mazindol tablets(Sandoz Pharmaceuticals, East Hanover, NJ, USA); 4.说明书-Sanorex(R), mazindol(Sandoz Pharmaceuticals Corporation, East Hanover, NJ); 5.说明书-VYVANSE(TM) oral capsules, lisdexamfetamine dimesylate oral capsules(New River Pharmaceuticals,Inc, Blacksburg, VA); 6.说明书-马吲哚片; 7.文献资料-Acta Neurol Scand,1979; 8.文献资料-Br Med J,1983; 9.文献资料-Clin Obstet Gynecol,2002; 10.文献资料-Curr Ther Res,1977; 11.文献资料-Drug Metab Dispos,1979; 12.文献资料-Med J Aust,1975; 13.文献资料-Practitioner,1977; 14.文献资料-Praxis,1976; 15.文献资料-Rocky Mountain Med J,1974; 点击展开全部文献

【参考文献】: 1.说明书-DA TSCAN(R) IV injection, ioflupane I 123 IV injection(GE Healthcare, Arlington Heights, IL); 2.说明书-Meridia(R), sibutramine hydrochloride monohydrate(Knoll Pharmaceutical Company, Mount Olive, NJ); 3.说明书-Sanorex(R), mazindol tablets(Sandoz Pharmaceuticals, East Hanover, NJ, USA); 4.说明书-Sanorex(R), mazindol(Sandoz Pharmaceuticals Corporation, East Hanover, NJ); 5.说明书-VYVANSE(TM) oral capsules, lisdexamfetamine dimesylate oral capsules(New River Pharmaceuticals,Inc, Blacksburg, VA); 6.说明书-马吲哚片; 7.文献资料-Acta Neurol Scand,1979; 8.文献资料-Br Med J,1983; 9.文献资料-Clin Obstet Gynecol,2002; 10.文献资料-Curr Ther Res,1977; 11.文献资料-Drug Metab Dispos,1979; 12.文献资料-Med J Aust,1975; 13.文献资料-Practitioner,1977; 14.文献资料-Praxis,1976; 15.文献资料-Rocky Mountain Med J,1974; 点击展开全部文献