甲哌卡因的作用与功效_甲哌卡因说明书

NMPA批准适应症

【药品名称】: 通用名称: 甲哌卡因; 英文名称: Mepivacaine; 其他名称: 甲哌酰卡因、卡波卡因、Mepivacainum、Polocaine

【适应症及用法用量】

用于口腔及牙科治疗中的局部浸润麻醉(神经传导阻滞型)。

剂型	规格
注射液	1.8ml:54mg

用法用量:: 人群: 成人

给药途径: 局部注射

用法用量详情: 3%注射液：通常一次1.8ml，不得超过5.4ml，使用频率不应高于一周1次。; 人群: 儿童

给药途径: 局部注射

用法用量详情: 通常一次0.0167ml/kg，但一次不能超过1.8ml，最大剂量为儿童体重(公斤)×1.33。6岁到14岁：1.6毫升，不超过3.3毫升。4到6岁：1.1毫升到2.2毫升，对4周岁以上儿童的用药剂量视患儿年龄，体重及所用具体治疗方式而定。4岁以下儿童禁用。

硬膜外阻滞麻醉。

剂型	规格
注射液	20ml：0.4g

用法用量:: 人群: 成人

给药途径: 硬膜外注射

用法用量详情: 应给予可产生预期效果的最小剂量。应分次给药，避免快速大量注射。对于未使用镇静药的正常身材的健康成人，推荐单次剂量(或一次麻醉过程中的总剂量)通常不超过400mg，质虚弱病人应该减小剂量。任何情况下，重复给药的间隔不应小于1.5小时。24小时的总给药量不应超过1000mg。; 人群: 老人

给药途径: 硬膜外注射

用法用量详情: 老年人应该减小剂量。; 人群: 儿童

给药途径: 硬膜外注射

用法用量详情: 应根据体重仔细计算占成人总剂量的百分比，儿童剂量不应超过5mg/kg-6mg/kg，尤其是体重小于13.6kg时。小于3岁或体重小于13.6kg的儿童，应使用小于2%(如0.5%～1.5%)的浓度。盐酸甲哌卡因的推荐浓度和剂量：2%浓度，10～20ml，200～400mg。

【参考文献】: 1.说明书-盐酸甲哌卡因注射液【法国赛普敦(SEPTODONT)公司】; 2.说明书-盐酸甲哌卡因注射液【辰欣药业股份有限公司】; 点击展开全部文献

【参考文献】: 1.说明书-Carbocaine(R), mepivacaine hydrochloride injection(Abbott Laboratories, North Chicago, IL); 2.说明书-Carbocaine(R), mepivacaine(Sanofi Winthrop, New York, NY); 3.说明书-Carbocaine(TM) solution for injection, Mepivacaine Hydrochloride solution for injection(Hospira Inc, Lake Forest, IL); 4.说明书-InnoPran XL(R) oral capsules, propranolol hydrochloride oral capsules(GlaxoSmithKline, Research Triangle Park, NC); 5.说明书-Nimbex(R), cisatracurium besylate injection(Glaxo Wellcome Inc., Research Triangle Park, NC); 6.说明书-Wydase(R), hyaluronidase(Wyeth Laboratories, Philadelphia, PA); 7.说明书-盐酸甲哌卡因注射液(SEPTODONT); 8.说明书-盐酸甲哌卡因注射液(辰欣药业股份有限公司); 9.FDA-Mepivacaine Hydrochloride Injection(Hospira, Inc.); 10.Lexicomp-Dental; 11.Lexicomp-Mepivacaine; 12.文献资料-Acta Anaesthesiol Scand,2000; 13.文献资料-Anesth Analg,1987; 14.文献资料-Anesth Analg,1996; 15.文献资料-Anesthesiology,1996; 16.文献资料-Anesthesiology,2002; 17.文献资料-Ann Emerg Med,1988; 18.文献资料-Can Anaesth Soc J,1971; 19.文献资料-Can J Anaesth,1993; 20.文献资料-Drugs,1984; 21.文献资料-Invest Ophthal,1974; 22.文献资料-JAMA,1971; 23.文献资料-Journal of the European Academy of Dermatology and Venereology - JEADV,2008; 24.文献资料-Reg Anesth Pain Med,1998; 点击展开全部文献

【参考文献】: 1.说明书-Carbocaine(R), mepivacaine(Sanofi Winthrop, New York, NY); 2.说明书-Carbocaine(R), mepivacaine hydrochloride injection(Abbott Laboratories, North Chicago, IL); 3.说明书-Carbocaine(TM) solution for injection, Mepivacaine Hydrochloride solution for injection(Hospira Inc, Lake Forest, IL); 4.说明书-InnoPran XL(R) oral capsules, propranolol hydrochloride oral capsules(GlaxoSmithKline, Research Triangle Park, NC); 5.说明书-Nimbex(R), cisatracurium besylate injection(Glaxo Wellcome Inc., Research Triangle Park, NC); 6.说明书-Wydase(R), hyaluronidase(Wyeth Laboratories, Philadelphia, PA); 7.说明书-盐酸甲哌卡因注射液(SEPTODONT); 8.说明书-盐酸甲哌卡因注射液(辰欣药业股份有限公司); 9.FDA-Mepivacaine Hydrochloride Injection(Hospira, Inc.); 10.Lexicomp-Dental; 11.Lexicomp-Mepivacaine; 12.文献资料-Acta Anaesthesiol Scand,2000; 13.文献资料-Anesthesiology,1996; 14.文献资料-Anesthesiology,2002; 15.文献资料-Anesth Analg,1987; 16.文献资料-Anesth Analg,1996; 17.文献资料-Ann Emerg Med,1988; 18.文献资料-Can Anaesth Soc J,1971; 19.文献资料-Can J Anaesth,1993; 20.文献资料-Drugs,1984; 21.文献资料-Invest Ophthal,1974; 22.文献资料-JAMA,1971; 23.文献资料-Journal of the European Academy of Dermatology and Venereology - JEADV,2008; 24.文献资料-Reg Anesth Pain Med,1998; 点击展开全部文献

【参考文献】: 1.说明书-Carbocaine(R), mepivacaine(Sanofi Winthrop, New York, NY); 2.说明书-Carbocaine(R), mepivacaine hydrochloride injection(Abbott Laboratories, North Chicago, IL); 3.说明书-Carbocaine(TM) solution for injection, Mepivacaine Hydrochloride solution for injection(Hospira Inc, Lake Forest, IL); 4.说明书-InnoPran XL(R) oral capsules, propranolol hydrochloride oral capsules(GlaxoSmithKline, Research Triangle Park, NC); 5.说明书-Nimbex(R), cisatracurium besylate injection(Glaxo Wellcome Inc., Research Triangle Park, NC); 6.说明书-Wydase(R), hyaluronidase(Wyeth Laboratories, Philadelphia, PA); 7.说明书-盐酸甲哌卡因注射液(SEPTODONT); 8.说明书-盐酸甲哌卡因注射液(辰欣药业股份有限公司); 9.FDA-Mepivacaine Hydrochloride Injection(Hospira, Inc.); 10.Lexicomp-Dental; 11.Lexicomp-Mepivacaine; 12.文献资料-Acta Anaesthesiol Scand,2000; 13.文献资料-Anesthesiology,1996; 14.文献资料-Anesthesiology,2002; 15.文献资料-Anesth Analg,1987; 16.文献资料-Anesth Analg,1996; 17.文献资料-Ann Emerg Med,1988; 18.文献资料-Can Anaesth Soc J,1971; 19.文献资料-Can J Anaesth,1993; 20.文献资料-Drugs,1984; 21.文献资料-Invest Ophthal,1974; 22.文献资料-JAMA,1971; 23.文献资料-Journal of the European Academy of Dermatology and Venereology - JEADV,2008; 24.文献资料-Reg Anesth Pain Med,1998; 点击展开全部文献